Senior Research Scientist - AZNJP00029890

4641001
  • Job type

    Temporary
  • Location

    Cambridge
  • Working Pattern

    Full-time
  • Specialism

    Life Sciences Manufacturing
  • Industry

    Pharmaceuticals
  • Pay

    Hourly Rate
  • Closing date

    10 Jan 2025

AZ currently require a Snr Research Scientist in mechanistic biology and profiling on an interim basis.

Senior Research Scientist - AZNJP00029890
In vitro Cellular Pharmacology, Mechanistic Biology and Profiling

Location – DISC, Cambridge, UK (on-site)
Duration – 12 months
Inside IR35

Be empowered to be innovative and creative where difference is valued
Join a place built on innovation and creativity. Where different views and perspectives are encouraged and valued. An environment that champions inclusion, and teams that reflect the diversity of the communities that we serve. It propels each of us forward, harnessing our differences to unlock challenges and bring new solutions. Fuel your curiosity and entrepreneurial spirit to uncover new insights that challenge conventions. Here we are forever pushing the boundaries as we feel comfortable spotting opportunities, making quick decisions and taking smart risks.

Who we are
Discovery Sciences is a multi-faceted department which drives early drug discovery across AstraZeneca’s global Research & Development portfolio. The successful candidate will be located at AstraZeneca’s vibrant R&D site in Cambridge, UK and will be part of Mechanistic Biology and Profiling, a team where we collaborate to support projects aiming to impact the lives of our patients. We are responsible for the generation of data that drives the chemistry in our projects as well as bespoke mechanism-of-action information studies in support of the Oncology, Cardiovascular and Renal Disease, Respiratory, Inflammation & Immunology and Neuroscience portfolios.


What you’ll do
In this laboratory-based position, you will deliver in vitro pharmacology and cell biology data to drug discovery projects to support both profiling and mechanism of action studies. You will be comfortable working as part of a cross functional team to interpret data and determine next steps to drive projects forwards. Your passion to follow the science will enable delivery of our exciting portfolio.


Examples of typical tasks
  • Deliver in vitro cellular profiling and mechanism of action data to drug discovery protects in support of both safety and efficacy.
  • Working as part of a cross functional team to interpret data and agree next steps to drive projects forwards.
  • Designing, performing and interpreting experiments to generate detailed mechanism-of-action studies for lead compounds.
  • Interaction across a broad range of therapeutic projects with the opportunity to represent the group at project team meetings.
  • Furthering your personal scientific visibility through internal and external presentations and publications.
  • Developing and evaluating new models to support both early-stage in vitro safety and efficacy pharmacology.

Essential for the role
Our team is a highly collaborative group, working to deliver both profiling and mechanistic data so the ability to combine delivery as well as bespoke experimental design, with a goal-oriented focused approach is crucial to be successful in the role.

  • Formal training and proven expertise (PhD + postdoc, or equivalent experience) in in vitro pharmacology, cell biology or a related setting with a sincere passion for science
  • Cellular biology and pharmacology techniques applied to compound profiling and mechanism of action studies
  • Future orientated with a desire to drive scientific and technical innovation
  • Strong analytical and communication skills
  • Proven external reputation in in vitro pharmacology & cellular biology gained through external presentation and publications in peer reviewed journals

Desirable for the role
  • Experience developing automated processes to deliver cellular data such as: high content imaging, flow cytometry or FLIPR
  • An understanding of the drug discovery process (either pharma or CRO) OR of working in an academic lab that has strong links with drug discovery




What you need to do now


If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now.

If this job isn't quite right for you, but you are looking for a new position, please contact us for a confidential discussion about your career.


For more detailed information, or to view other vacancies with this organisation, please visit our dedicated recruitment website  https://webmicrosites.hays.co.uk/web/tempwork_astrazeneca

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Talk to Owen Lavers, the specialist consultant managing this position

Located in Leicester, 1st & 2nd Floor, 2 Colton SquareTelephone 0116 261 5048
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