Senior Scientist - Mass Spec / Proteomics

4646014
  • Job type

    Contract
  • Location

    Oxford
  • Working Pattern

    Full-time
  • Specialism

    Scientific And Engineering
  • Industry

    Scientific and R&D
  • Pay

    £34 - £36 per hour

Senior Scientist | Mass Spectrometry | Proteomics | Oxford | Interim Contract

Your new company

A global biotechnology company that researches and develops biological therapeutics for infectious and autoimmune diseases. They are a leading ATMP-focused company that is going through a huge period of growth.


Your new role

  • Characterise and identify impurities in drug substances and products.
  • Identify protein sequences and post-translational modifications, such as glycosylation.
  • Assist in the development of drug substances and products by characterising process intermediates.
  • Develop characterisation methods for ImmTAX and other products, including peptide mapping (LC-MS/MS) and intact mass analysis.
  • Design and execute biochemical characterisations, chemical stability assessments, and comparability studies of biologics and drug products.
  • Contribute to the creation of study protocols and reports.
  • Independently test and lead lines of investigation.
  • Propose new experiments based on emerging data and relevant information.
  • Set work priorities for oneself and team-based projects. Make prioritisation decisions based on team, department, and project goals using direct evidence and experience.
  • Share technical knowledge with the team and across departments. Act as a mentor, provide scientific knowledge, and analyse new techniques and theories to advance company practices. Share insights with department leaders.
  • Ensure laboratory records and information are up-to-date, timely, and meets required standards. Support and encourage others in achieving these standards.
  • Offer technical guidance on laboratory equipment usage to team members.
  • Communicate and present research findings at meetings with colleagues, senior management, and partners.

What you'll need to succeed

  • Be able to develop HPLC-based peptide mapping methods and characterise recombinant proteins or antibodies using mass spectrometry.
  • Conduct glycosylation analysis for recombinant proteins or antibodies.
  • Coordinate extensive testing of protein biomolecules independently.
  • Characterise proteins expressed in both microbial and mammalian systems.
  • Understand post-translational modifications in biological systems.
  • Work in a bench-based biopharmaceutical laboratory environment.
  • Have expertise in one or more of the following areas: electrophoresis, chromatography, mass spectrometry.
  • Confident in developing assays and being able to execute related tasks.
  • Actively participate and contribute in a diverse team environment.
  • Propose and implement changes in working practices to improve efficiency, and support teams during transitions.
  • Present detailed scientific findings and papers to internal and external audiences.

What you'll get in return

  • Flexible working options
  • Competitive rate of pay

What you need to do now

If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now.

If this job isn't quite right for you, but you are looking for a new position, please contact us for a confidential discussion about your career.

Apply for this job

Talk to Izzy De Meo, the specialist consultant managing this position

Located in London-City, 5th Floor, 107 Cheapside, Telephone +44 333 010 6320
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